Peptide Chemistry & Forms / Technical guide

CJC-1295 With DAC vs Without DAC: Identity Checklist

An identity checklist for distinguishing CJC-1295 with DAC from products described as without DAC or Mod GRF(1-29).

Reviewed August 2026Buyer & quality briefingResearch supply context
Essential point

With-DAC and without-DAC materials are not interchangeable descriptions. The Drug Affinity Complex changes molecular design and expected identity evidence.

01 / Review framework

What procurement and laboratory teams should review

01

Write DAC status in the specification

02

Request sequence or an unambiguous molecular description

03

Compare theoretical and observed mass for the correct form

04

Prevent shortened labels from obscuring identity

02 / Technical interpretation

Define the molecular form before comparing offers

Sequence alone may not fully define a peptide material. Termini, modifications, disulfide pattern, counterion, hydration state and presentation can affect molecular-weight calculations, analytical reporting, solubility and handling.

  • Record sequence, termini and every modification explicitly.
  • State the requested salt or counterion form.
  • Treat solubility and stability as material- and condition-specific.
01Specify molecular structure
02Choose material form
03Align testing and calculations
04Confirm handling plan
03 / Supplier discussion

Questions to resolve before quotation or release

  1. Does the document state DAC status?
  2. How is Mod GRF terminology defined?
  3. Which mass and identity method apply?
HK PEPTIDES project note

Resolve variant naming before quotation so label, COA and molecule align.

04 / Technical references

Source material and further reading

This guide is informed by the following primary guidance and established technical resources. Always confirm the current version and its applicability to your material and jurisdiction.

  1. ICH / FDAQ2(R1) Validation of Analytical Procedures
  2. BachemPeptide Handling, Salt Forms and Technical FAQ
  3. United States PharmacopeiaReference Standards to Support Quality of Synthetic Peptide Therapeutics
Research use only

HK PEPTIDES materials are supplied for laboratory research and documentation workflows only. They are not intended for human consumption, diagnostic use, therapeutic use, veterinary use or clinical application.

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